Drug discrimination: stimulus control during repeated testing in extinction.

Drug discrimination: stimulus control during repeated testing in extinction.

Rats were trained, under a two-lever drug-discrimination procedure, to respond differentially depending upon whether lorazepam (1.0 mg/kg) or no injection had been administered before the session. Responses on the appropriate lever produced a food pellet under a modified fixed-ratio (FR) 10 schedule, in which the 10 responses had to be emitted consecutively. In reinforcement tests, completing a...

'Subjective lengthening' during repeated testing of a simple temporal discrimination.

Three experiments investigated behavioural changes, using a temporal generalization paradigm with human subjects, resulting from repeated testing without feedback. In Experiment 1, different groups received five initial presentations of a 400 ms 500 Hz tone, or a 400 ms 14×14 cm blue square, identified as having a standard duration, then received blocks of testing where stimuli with durations s...

Using action dynamics to assess competing stimulus control during stimulus equivalence testing.

Previous studies have identified potential sources of competing stimulus control in tests for stimulus equivalence. The present experiment employed the Nintendo Wii remote (Wiimote®) to investigate whether such competition would affect suboperant action dynamics (e.g., topographies of equivalence responses). Following one-to-many training on conditional discriminations sufficient to establish t...

Neurocognitive processes during repeated study and repeated testing An fMRI experiment on the testing effect

Drug-drug discrimination: stimulus properties of drugs of abuse upon a serotonergic-dopaminergic continuum.

Ten male N/Nih rats were trained to discriminate between the interoceptive cues produced by the purportedly dopaminergically-mediated drug d-amphetamine at 0.4 mg/kg intraperitoneally administered 20 min prior to training and those produced by the purportedly serotonergically-active agent norfenfluramine at 0.7 mg/kg. Once this discrimination was successfully acquired, the rats were tested with...